Synopsis This book which is based on around 8000 references from the Vedas Upanisads, Puranas, Darsanas & major Ayurvedic texts, thorough analysis of the principles which form building blocks of the universe, tries to make an approach in the realm of the ultimate reality. It is a maiden attempt to show that the views about the principles of the universe, expressed by various schools of thought are dissident, in fact they are describing the same principles in slightly different style. Comprehensive views on the evolution, existence and dissolution of the universe are presented and its is revealed that Panchamahabhuta and the Brahma-Avyakta are the principles behind this panorama. With the help of latest theories in physics it is proved that these views are totally supported even by Modern Sciences. The book is expected to be a thought provoking pleasure for students, research workers and teachers of Ayurveda and also for all interested in oriental sciences.