Synopsis The word Prameha means passage of large quantities of urine or passage in urine of one or more products of metabolism which may or may not be a normal constituent of urine in large amount. Prameha includes a number of metabolic disorders associated with the characteric urinary abnormality. The examination of urine gives us a clue to the diagnosis of the particular type of abnormality in Prameha, e.g. in Kalameha, the urine appears black in odour and corresponds to alcaptonuria. Udakameha where urine is water like corresponds to diabetes insipidus. Twenty different types of Prameha are described and their prognosis and treatment are given. This book also gives pathogenesis, treatment and complications of Madhumeha i.e. Diabetes mellitus. This book will be useful to patients as well as physicians and Vaidyas treating diabetes mellitus and metabolic conditions charactered by some abnormality of urine.