Synopsis The present book molecular biophysics deals with biochemical, biophysical, physical and biological aspects of macromolecules. The material covers a broad range of sophistication so that the text can be used by the students of biotechnology and engineering. It should also be valuable to general scientific readers who simply wish to become familiar with the field as well as to experienced readers in biophysical area. This book also demonstrates that how biophysical techniques and principles are used in concert to gain an understanding of the behaviour and properties of biological macromolecules. The focus is on the conformational changes in macromolecules and there interactions.