Synopsis The Neem tree (Azadirachta indica A. Juss) is a tropical evergreen plant native to east India and Burma. It grows in much of Southeast Asia and West Africa. In modern research concerns it gains equally high preference due to the potential of using neem derivatives such as leaf extract, oil, seed kernel extract, for preparation of environment friendly `soft-herbicides'. Not only these conventional approaches limit the potential exploitation of the neem plant, but also some new fascinating areas were open for further research, and one of them is to explore the entophytic microbial diversity.