The book is divided into 111 chapters that are further separated by 14 sections for an easy comprehension of the subject. Section 1 (General Principles) deals with general principles of critical care, including severity scoring, and monitoring various aspects of ventilation, ECMO, sugar control, sedoanalgesia, delirium, etc. Section 2 (Cardiovascular System) deals with all aspects of acute cardiovascular pathology requiring ICU admission. With the early diagnosis and shorter door to balloon or needle time even in developing countries, ACS and aortic dissections are reaching to hospitals with subsequent admission in ICU. We have especially included the newer antiplatelets, antithrombotic agents as they are new arrivals in developing countries. Section 3 (Respiratory System) presents critical care in cases of acute respiratory syndrome, respiratory failure, obstructive pulmonary diseases, severe asthma, pneumonia, hemoptysis, pleural effusion, and pneumothorax. Section 4 (Renal System) is on acute kidney infection and renal replacement therapy. Section 5 (Gastrointestinal Tract, Pancreas and Hepatobiliary System) also contains chapters on how to approach elevated live enzymes and portal hypertension, along with the common ICU issues related to GI, pancreas and liver. Section 6 (Neurology) starts with the approach to an unconscious patient and covers the common neurocritical problems like stroke, seizures, infections, and neuromuscular disorders requiring ICU admission. Section 7 (Endocrine) covers the sugar control, DI and SIADH, thyroid and adrenals. Section 8 (Post-surgical Critical Care) is a relatively new section for a critical care book where the chapters are jointly written by the surgeons and critical care specialists in that field and covers neuro, cardiac, vascular, thoracic, and transplants with the discussion on immunosuppression. Section 9 (Obstetric Critical Care) and Section 10 (Hematology, Rheumatology and Oncology) are poorly recognized and poorly developed field in the underdeveloped and developing countries, so these two sections have special significance in the book. Section 11 (Infections) deals with bacterial, viral, fungal, rickettsial infections, including community-acquired and nosocomial. Evaluation of fever in ICU and principles of antimicrobial therapy, including pharmacokinetics and pharmacodynamics are also discussed in this section. Section 12 (Toxicology and Environmental Injuries) contains chapters on poisoning, snakebites and environmental injuries needing critical care.