The Susruta-Samhita is one of the twin compendia of Ayurveda encompassing all the aspects prevalent traditionally in India and abroad since the earliest times. It represents faithfully the school of surgery which made significant contributions to principles and techniques of surgery which are surprisingly applicable even in modern era. It presents the status of ancient Indian surgery comprehensively and as such is in great demand among scholars all over the world. The present edition of the Susruta-Samhita is singular in the sense that, besides presenting faithful translation of the text, it brings forth, for the first time, the English translation of the Nibandha-Sangraha commentary by Dalhana who is regarded as the authority on the subject. The commentary supplements the text in many respects and as such proves an essential tool for understanding the Samhita clearly and fully. Notes are also given here and there to elaborate the ideas with critical analysis. The text has also been checked and modified according to the readings accepted by Dalhana. Plants and other substances are also identified as interpreted by Dalhana. At the end of the text appendices are given which are very useful.